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Bioinformatics is increasingly becoming a mainstay of biological research. As such, consideration needs to be placed on effective planning of experiments with the end results in mind. From grant proposals to power calculations, we are on hand to guide experimental design to ensure you get the most from your sequencing experiments.
New and existing genetic data can be exploited now more than ever. As well as providing a high resolution genetic snapshot of an organism, the field of bioinformatics is constantly evolving to enable us to mine sequencing data for increasingly novel insights. Below are some of the bioinformatic approaches we have experience in and can offer for your research.
- 16s Ribosomal sequencing
- Polymorphism detection
- Genome assembly
- Genome annotation
- BLAST analysis
- Transposon Element Analysis
- Source analysis of metagenome findings
Our team has experience in hundreds of RNAseq analyses across a range of applications. From novel assemblies to established genomes, we are on hand to help you show how your samples are dynamically responding to treatments.
- Differential gene expression
- Alternative splicing analysis
- Pipeline building
- Transcript annotation
Next generation sequencing data can be dense and difficult to unpick. Initial work on data visualisation required graphs to be built up from scratch. There are now a variety of visualisation strategies for next generation sequencing data. Whether there are any established graphical strategies you had in mind, or wanted to explore novel ways of displaying your data, we can help.
- GNUPlot
- RStudio
- Gene ontology
- Gene set enrichment analysis
- Clustering analysis
- Pathway analysis
We understand the bespoke nature of research and enjoy the challenges associated. So get in touch today to see if we can offer support with any other pipelines you might be keen on exploring.
InSilico Consulting has proudly worked alongside Bristol Genomics Facility at the University of Bristol.
Bristol Genomics offer state of the art genomics and transcriptomics services. Jane Coghill and Christy Waterfall have a wealth of experience between them in next generation sequencing techniques and are on hand to offer a range of sequencing options.
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